Package: multipleOutcomes
Title: Joint Covariance and Treatment-Effect Tests for Multiple
        Outcomes
Version: 0.18.0
Authors@R: 
    person("Han", "Zhang", , "zhangh.ustc@gmail.com", role = c("aut", "cre"))
Description: Fits generalized linear models, Cox proportional-hazards
        models, log-rank tests, generalized estimating equations, mixed
        models with repeated measures, Kaplan-Meier curves, quantile
        differences, and hierarchical net-benefit (win-difference) and
        log win-ratio statistics jointly across multiple endpoints, and
        returns the full asymptotic covariance matrix linking them.
        Implements PATED (Prognostic Assisted Treatment Effect
        Detection), a randomized-trial method that exploits balanced
        prognostic covariates to tighten standard errors and increase
        statistical power without introducing bias.
URL: https://github.com/zhangh12/multipleOutcomes,
        https://zhangh12.github.io/multipleOutcomes/
BugReports: https://github.com/zhangh12/multipleOutcomes/issues
License: MIT + file LICENSE
Encoding: UTF-8
Roxygen: list(markdown = TRUE)
Imports: dplyr, ggplot2, ggpubr, mmrm (>= 0.3.15), mvtnorm, rlang,
        sandwich, stringr, survival, tidyr, tidyselect
Suggests: asaur, coin, iBST, invGauss, JM, knitr, momentfit, numDeriv,
        pec, rmarkdown, testthat (>= 3.0.0)
Depends: R (>= 3.5)
LazyData: true
Config/roxygen2/version: 8.0.0
Config/pak/sysreqs: cmake make libicu-dev
Repository: https://zhangh12.r-universe.dev
Date/Publication: 2026-06-13 01:18:50 UTC
RemoteUrl: https://github.com/zhangh12/multipleoutcomes
RemoteRef: HEAD
RemoteSha: 3bfc7d361d5bca858dce7f49511961f47319fd42
NeedsCompilation: yes
Packaged: 2026-06-13 02:49:21 UTC; root
Author: Han Zhang [aut, cre]
Maintainer: Han Zhang <zhangh.ustc@gmail.com>